The Neverending PR Cluelessness of Pharma
Once again, pharmaceutical companies demonstrate world-class stupidity when it comes to averting negative PR. The latest example comes in the form of retired teacher and sufferer of Parkinson’s disease, Suzanne Davenport, whose story was reported yesterday by Sarah Rubenstein of the Wall Street Journal (and also at the WSJ’s Health Blog). Ms. Davenport and her family are currently seeking compensation from Titan Pharmaceuticals and Bayer HealthCare Pharmaceuticals, codevelopers of Spheramine* brain implants, which Ms. Davenport received in January 2005 as part of an investigational phase 2 clinical study.
Following the procedure, Ms. Davenport experienced a precipitous, unexpected decline in her clinical status, which has since required premature, continued skilled nursing care. In the WSJ article, both Ms. Davenport’s former neurologist, UCLA Spheramine-study investigator Jeff Bronstein, MD, PhD, and her current
And now in predictable fashion, Ms. Davenport’s family has retained the services of an attorney, Stephen R. Pappas, and are suing Titan, Bayer HealthCare, and the regents of the
*Spheramine consists of levodopa-producing human retinal pigment epithelial cells attached to gelatin microcarriers, which are stereotactically implanted into the brain (the postcommissural putamen to be exact). The intention is that the continuous delivery of levodopa to the striatal pathway of the brain will better approximate the physiologic restoration of levodopa in PD than standard, oral levodopa therapy for the disease.
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Spheramine brain implants improve mobility in moderate-to-advanced Parkinson's disease, according to a phase 1/2 open-label pilot study in 6 patients. A 4-year follow-up report* of the study was presented April 29 at the annual meeting of the American Read More




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