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    <title>Pathophilia</title>
    <link rel="alternate" type="text/html" href="http://bmartinmd.com/" />
    <link rel="self" type="application/atom+xml" href="http://bmartinmd.com/atom.xml" />
    <id>tag:bmartinmd.com,2007-10-12://1</id>
    <updated>2010-03-15T18:06:11Z</updated>
    <subtitle>For the love of disease.</subtitle>
    <generator uri="http://www.sixapart.com/movabletype/">Movable Type Publishing Platform 4.01</generator>

<entry>
    <title>Geiers&apos; Studies Discredited in Federal Vaccine Opinions</title>
    <link rel="alternate" type="text/html" href="http://bmartinmd.com/2010/03/geier-studies-discredited-in-v.html" />
    <id>tag:bmartinmd.com,2010://1.792</id>

    <published>2010-03-15T17:45:06Z</published>
    <updated>2010-03-15T18:06:11Z</updated>

    <summary><![CDATA[ As just about everyone knows by now, the Special Masters of the US Court of Federal Claims handed down their decisions on Friday, which deny a causative link between the vaccine preservative thimerosal&nbsp;and autism in 3 test cases. Among...]]></summary>
    <author>
        <name>bmartin</name>
        <uri>http://www.pathophilia.com</uri>
    </author>
    
        <category term="Epidemiology" scheme="http://www.sixapart.com/ns/types#category" />
    
        <category term="Health care" scheme="http://www.sixapart.com/ns/types#category" />
    
        <category term="Infectious diseases" scheme="http://www.sixapart.com/ns/types#category" />
    
        <category term="Legal" scheme="http://www.sixapart.com/ns/types#category" />
    
        <category term="Pediatrics" scheme="http://www.sixapart.com/ns/types#category" />
    
    <category term="autism" label="autism" scheme="http://www.sixapart.com/ns/types#tag" />
    <category term="vaccination" label="vaccination" scheme="http://www.sixapart.com/ns/types#tag" />
    
    <content type="html" xml:lang="en" xml:base="http://bmartinmd.com/">
        <![CDATA[ As just about everyone knows by now, the Special Masters of the US Court of Federal Claims handed down their decisions on Friday, which deny a causative link between the vaccine preservative thimerosal&nbsp;and autism in 3 test cases. Among...]]>
        
    </content>
</entry>

<entry>
    <title>Kick-Back Friday: #108</title>
    <link rel="alternate" type="text/html" href="http://bmartinmd.com/2010/03/kickback-friday-108.html" />
    <id>tag:bmartinmd.com,2010://1.791</id>

    <published>2010-03-12T23:03:47Z</published>
    <updated>2010-03-13T20:30:58Z</updated>

    <summary><![CDATA[ On the basis of his success with The Manchurian Candidate (1962), director John Frankenheimer was able to assemble a similar behind-the scenes crew for another B&amp;W&nbsp;political thriller, Seven Days in May (1964). This time, however, Rod Serling (not George...]]></summary>
    <author>
        <name>bmartin</name>
        <uri>http://www.pathophilia.com</uri>
    </author>
    
        <category term="Kick-Back Friday" scheme="http://www.sixapart.com/ns/types#category" />
    
    <category term="kickbackfriday" label="Kick-Back Friday" scheme="http://www.sixapart.com/ns/types#tag" />
    <category term="movie" label="movie" scheme="http://www.sixapart.com/ns/types#tag" />
    
    <content type="html" xml:lang="en" xml:base="http://bmartinmd.com/">
        <![CDATA[ On the basis of his success with The Manchurian Candidate (1962), director John Frankenheimer was able to assemble a similar behind-the scenes crew for another B&amp;W&nbsp;political thriller, Seven Days in May (1964). This time, however, Rod Serling (not George...]]>
        
    </content>
</entry>

<entry>
    <title>In Defense of (Some) High-Tech Screening Tests in POTOS</title>
    <link rel="alternate" type="text/html" href="http://bmartinmd.com/2010/03/in-defense-high-tech-in-potos.html" />
    <id>tag:bmartinmd.com,2010://1.790</id>

    <published>2010-03-12T16:37:39Z</published>
    <updated>2010-03-13T20:27:30Z</updated>

    <summary><![CDATA[ Thanks to a new&nbsp;editorial&nbsp;at&nbsp;the Archives of Internal Medicine&nbsp;web site, much is being made of the high-end technology that was used to recently examine POTOS's health status. At issue, according to cardiologist&nbsp;Rita Redberg, the journal's editor,&nbsp;is the ill-advised use of...]]></summary>
    <author>
        <name>bmartin</name>
        <uri>http://www.pathophilia.com</uri>
    </author>
    
        <category term="Health care" scheme="http://www.sixapart.com/ns/types#category" />
    
    <category term="obama" label="Obama" scheme="http://www.sixapart.com/ns/types#tag" />
    
    <content type="html" xml:lang="en" xml:base="http://bmartinmd.com/">
        <![CDATA[ Thanks to a new&nbsp;editorial&nbsp;at&nbsp;the Archives of Internal Medicine&nbsp;web site, much is being made of the high-end technology that was used to recently examine POTOS's health status. At issue, according to cardiologist&nbsp;Rita Redberg, the journal's editor,&nbsp;is the ill-advised use of...]]>
        
    </content>
</entry>

<entry>
    <title>On Medicare Cut, Senate Kicks the Can Again</title>
    <link rel="alternate" type="text/html" href="http://bmartinmd.com/2010/03/senate-delays-medicare-cut-again.html" />
    <id>tag:bmartinmd.com,2010://1.789</id>

    <published>2010-03-11T16:44:17Z</published>
    <updated>2010-03-13T20:25:04Z</updated>

    <summary><![CDATA[ Yesterday the&nbsp;Senate passed another bill&nbsp;to postpone the mandated 21%&nbsp;reduction in Medicare reimbursement to physicians. The $140-million bill, passed by majority Democrats,*&nbsp;delays the draconian Medicare cut to October 1st and also extends unemployment benefits, COBRA subsidies, and state funding through...]]></summary>
    <author>
        <name>bmartin</name>
        <uri>http://www.pathophilia.com</uri>
    </author>
    
        <category term="Legislation" scheme="http://www.sixapart.com/ns/types#category" />
    
    <category term="medicare" label="Medicare" scheme="http://www.sixapart.com/ns/types#tag" />
    
    <content type="html" xml:lang="en" xml:base="http://bmartinmd.com/">
        <![CDATA[ Yesterday the&nbsp;Senate passed another bill&nbsp;to postpone the mandated 21%&nbsp;reduction in Medicare reimbursement to physicians. The $140-million bill, passed by majority Democrats,*&nbsp;delays the draconian Medicare cut to October 1st and also extends unemployment benefits, COBRA subsidies, and state funding through...]]>
        
    </content>
</entry>

<entry>
    <title>FDA Approves Botox for Arm Spasticity in Adults; Allergan&apos;s Case Against Govt Still Active</title>
    <link rel="alternate" type="text/html" href="http://bmartinmd.com/2010/03/fda-approves-botox-for-spasticity.html" />
    <id>tag:bmartinmd.com,2010://1.788</id>

    <published>2010-03-10T16:03:28Z</published>
    <updated>2010-03-10T17:26:27Z</updated>

    <summary><![CDATA[ Yesterday the FDA approved Botox (onabotulinumtoxin A; Allergan)&nbsp;to treat&nbsp;distal arm spasticity in adults.* The approval was based on results from at least 3 trials in&nbsp;a total of 305&nbsp;people&nbsp;with arm spasticity&nbsp;after stroke. Two of the 3&nbsp;studies have been published in...]]></summary>
    <author>
        <name>bmartin</name>
        <uri>http://www.pathophilia.com</uri>
    </author>
    
        <category term="Legal" scheme="http://www.sixapart.com/ns/types#category" />
    
        <category term="Neurology" scheme="http://www.sixapart.com/ns/types#category" />
    
        <category term="Pharma" scheme="http://www.sixapart.com/ns/types#category" />
    
    <category term="botulinumtoxin" label="botulinum toxin" scheme="http://www.sixapart.com/ns/types#tag" />
    <category term="fdaapproval" label="FDA approval" scheme="http://www.sixapart.com/ns/types#tag" />
    
    <content type="html" xml:lang="en" xml:base="http://bmartinmd.com/">
        <![CDATA[ Yesterday the FDA approved Botox (onabotulinumtoxin A; Allergan)&nbsp;to treat&nbsp;distal arm spasticity in adults.* The approval was based on results from at least 3 trials in&nbsp;a total of 305&nbsp;people&nbsp;with arm spasticity&nbsp;after stroke. Two of the 3&nbsp;studies have been published in...]]>
        
    </content>
</entry>

<entry>
    <title>Alzheimer Disease: Brace, Brace, Brace for the Aging Baby Boomer!</title>
    <link rel="alternate" type="text/html" href="http://bmartinmd.com/2010/03/alzheimer-disease-in-us.html" />
    <id>tag:bmartinmd.com,2010://1.787</id>

    <published>2010-03-09T16:51:17Z</published>
    <updated>2010-03-14T17:02:14Z</updated>

    <summary><![CDATA[ The Alzheimer's Association has a new report on the large and growing effect of&nbsp;Alzheimer disease and other dementias&nbsp;on Americans. Here's the distillation: AD is the most common cause of dementia, affecting 5.3 million Americans (1.7% of the current US...]]></summary>
    <author>
        <name>bmartin</name>
        <uri>http://www.pathophilia.com</uri>
    </author>
    
        <category term="Epidemiology" scheme="http://www.sixapart.com/ns/types#category" />
    
        <category term="Health care" scheme="http://www.sixapart.com/ns/types#category" />
    
        <category term="Neurology" scheme="http://www.sixapart.com/ns/types#category" />
    
        <category term="Neuropsychiatry" scheme="http://www.sixapart.com/ns/types#category" />
    
    <category term="alzheimersdisease" label="Alzheimer&apos;s disease" scheme="http://www.sixapart.com/ns/types#tag" />
    <category term="dementia" label="dementia" scheme="http://www.sixapart.com/ns/types#tag" />
    
    <content type="html" xml:lang="en" xml:base="http://bmartinmd.com/">
        <![CDATA[ The Alzheimer's Association has a new report on the large and growing effect of&nbsp;Alzheimer disease and other dementias&nbsp;on Americans. Here's the distillation: AD is the most common cause of dementia, affecting 5.3 million Americans (1.7% of the current US...]]>
        
    </content>
</entry>

<entry>
    <title>&quot;Son of Rituxan&quot; in Peril</title>
    <link rel="alternate" type="text/html" href="http://bmartinmd.com/2010/03/son-of-rituxan-in-peril.html" />
    <id>tag:bmartinmd.com,2010://1.786</id>

    <published>2010-03-08T16:28:53Z</published>
    <updated>2010-03-14T17:03:22Z</updated>

    <summary><![CDATA[ Trials of the monoclonal antibody ocrelizumab, a humanized version of the uber-mAb rituximab (Rituxan; Genentech/Biogen Idec), in rheumatoid arthritis and lupus&nbsp;have been halted because of drug-related infections and deaths.&nbsp;News of the&nbsp;grave snag in the mAb's phase 3 development (which...]]></summary>
    <author>
        <name>bmartin</name>
        <uri>http://www.pathophilia.com</uri>
    </author>
    
        <category term="Pharma" scheme="http://www.sixapart.com/ns/types#category" />
    
    <category term="monoclonalantibody" label="monoclonal antibody" scheme="http://www.sixapart.com/ns/types#tag" />
    <category term="multiplesclerosis" label="multiple sclerosis" scheme="http://www.sixapart.com/ns/types#tag" />
    
    <content type="html" xml:lang="en" xml:base="http://bmartinmd.com/">
        <![CDATA[ Trials of the monoclonal antibody ocrelizumab, a humanized version of the uber-mAb rituximab (Rituxan; Genentech/Biogen Idec), in rheumatoid arthritis and lupus&nbsp;have been halted because of drug-related infections and deaths.&nbsp;News of the&nbsp;grave snag in the mAb's phase 3 development (which...]]>
        
    </content>
</entry>

<entry>
    <title>Kick-Back Friday: #107</title>
    <link rel="alternate" type="text/html" href="http://bmartinmd.com/2010/03/kickback-friday-107.html" />
    <id>tag:bmartinmd.com,2010://1.785</id>

    <published>2010-03-05T22:07:13Z</published>
    <updated>2010-03-05T22:47:12Z</updated>

    <summary><![CDATA[ Raw Deal (1948): Underappreciated noir from director Anthony Mann,* with moody voiceover narration from Claire Trevor,&nbsp;the Queen of Noir. A northern California setting provides the fog. The story: Homme fatale Joe&nbsp;(Dennis O'Keefe)&nbsp;takes the prison rap for a crime boss,...]]></summary>
    <author>
        <name>bmartin</name>
        <uri>http://www.pathophilia.com</uri>
    </author>
    
        <category term="Kick-Back Friday" scheme="http://www.sixapart.com/ns/types#category" />
    
    <category term="kickbackfriday" label="Kick-Back Friday" scheme="http://www.sixapart.com/ns/types#tag" />
    <category term="movie" label="movie" scheme="http://www.sixapart.com/ns/types#tag" />
    
    <content type="html" xml:lang="en" xml:base="http://bmartinmd.com/">
        <![CDATA[ Raw Deal (1948): Underappreciated noir from director Anthony Mann,* with moody voiceover narration from Claire Trevor,&nbsp;the Queen of Noir. A northern California setting provides the fog. The story: Homme fatale Joe&nbsp;(Dennis O'Keefe)&nbsp;takes the prison rap for a crime boss,...]]>
        
    </content>
</entry>

<entry>
    <title>DTC Trends: Pregunte a su doctor</title>
    <link rel="alternate" type="text/html" href="http://bmartinmd.com/2010/03/pregunte-a-su-doctor.html" />
    <id>tag:bmartinmd.com,2010://1.784</id>

    <published>2010-03-05T15:12:53Z</published>
    <updated>2010-03-05T16:37:49Z</updated>

    <summary><![CDATA[Pharma's&nbsp;financial layout in 2009&nbsp;for DTC ads remained, for all practical purposes, stable, when compared with 2008's numbers. According&nbsp;to the latest Nielson data, by way of MM&amp;M,&nbsp;a total of $4.5 billion was shelled out by drug companies for ads on TV...]]></summary>
    <author>
        <name>bmartin</name>
        <uri>http://www.pathophilia.com</uri>
    </author>
    
        <category term="Marketing" scheme="http://www.sixapart.com/ns/types#category" />
    
        <category term="Pharma" scheme="http://www.sixapart.com/ns/types#category" />
    
    <category term="marketing" label="marketing" scheme="http://www.sixapart.com/ns/types#tag" />
    
    <content type="html" xml:lang="en" xml:base="http://bmartinmd.com/">
        <![CDATA[Pharma's&nbsp;financial layout in 2009&nbsp;for DTC ads remained, for all practical purposes, stable, when compared with 2008's numbers. According&nbsp;to the latest Nielson data, by way of MM&amp;M,&nbsp;a total of $4.5 billion was shelled out by drug companies for ads on TV...]]>
        
    </content>
</entry>

<entry>
    <title>The Taking of Absence Epilepsy One Two Three</title>
    <link rel="alternate" type="text/html" href="http://bmartinmd.com/2010/03/ethosuximide-preferred-rx.html" />
    <id>tag:bmartinmd.com,2010://1.783</id>

    <published>2010-03-04T15:54:53Z</published>
    <updated>2010-03-04T17:45:37Z</updated>

    <summary> The most common, identifiable form of pediatric epilepsy, absence seizures (formerly known as petit mal seizures) were first described in the early 18th century by (you guessed it) a French guy. Effective and relatively safe pharmacologic treatment for the...</summary>
    <author>
        <name>bmartin</name>
        <uri>http://www.pathophilia.com</uri>
    </author>
    
        <category term="Neurology" scheme="http://www.sixapart.com/ns/types#category" />
    
        <category term="Neuropsychiatry" scheme="http://www.sixapart.com/ns/types#category" />
    
        <category term="Pediatrics" scheme="http://www.sixapart.com/ns/types#category" />
    
        <category term="Pharma" scheme="http://www.sixapart.com/ns/types#category" />
    
    <category term="epilepsy" label="epilepsy" scheme="http://www.sixapart.com/ns/types#tag" />
    
    <content type="html" xml:lang="en" xml:base="http://bmartinmd.com/">
         The most common, identifiable form of pediatric epilepsy, absence seizures (formerly known as petit mal seizures) were first described in the early 18th century by (you guessed it) a French guy. Effective and relatively safe pharmacologic treatment for the...
        
    </content>
</entry>

<entry>
    <title>Dimebon Tanks (Along With Medivation Stock) in Phase 3 Alzheimer Trial</title>
    <link rel="alternate" type="text/html" href="http://bmartinmd.com/2010/03/dimebon-tanks-phase-3.html" />
    <id>tag:bmartinmd.com,2010://1.782</id>

    <published>2010-03-03T15:27:14Z</published>
    <updated>2010-03-03T16:16:03Z</updated>

    <summary> Someday I&apos;m going to learn to capitalize on the overblown expectations and inevitable letdown of AD drug development. Dimebon (latrepirdine), the nonselective antihistamine that Pfizer shelled out millions for, failed to improve cognition or global functioning in a placebo-controlled...</summary>
    <author>
        <name>bmartin</name>
        <uri>http://www.pathophilia.com</uri>
    </author>
    
        <category term="Neurology" scheme="http://www.sixapart.com/ns/types#category" />
    
        <category term="Neuropsychiatry" scheme="http://www.sixapart.com/ns/types#category" />
    
        <category term="Pharma" scheme="http://www.sixapart.com/ns/types#category" />
    
    <category term="alzheimersdisease" label="Alzheimer&apos;s disease" scheme="http://www.sixapart.com/ns/types#tag" />
    <category term="pharma" label="pharma" scheme="http://www.sixapart.com/ns/types#tag" />
    <category term="phase3trial" label="phase 3 trial" scheme="http://www.sixapart.com/ns/types#tag" />
    
    <content type="html" xml:lang="en" xml:base="http://bmartinmd.com/">
         Someday I&apos;m going to learn to capitalize on the overblown expectations and inevitable letdown of AD drug development. Dimebon (latrepirdine), the nonselective antihistamine that Pfizer shelled out millions for, failed to improve cognition or global functioning in a placebo-controlled...
        
    </content>
</entry>

<entry>
    <title>Bunning Still Blocking Extension of Medicare Reimbursement</title>
    <link rel="alternate" type="text/html" href="http://bmartinmd.com/2010/03/bunning-still-blocking-extension.html" />
    <id>tag:bmartinmd.com,2010://1.781</id>

    <published>2010-03-02T16:45:33Z</published>
    <updated>2010-03-03T20:50:46Z</updated>

    <summary><![CDATA[ Senator Bunning (R-KY) remains steadfast in his one-person crusade to block the passage of a bandaid bill that would extend unemployment benefits and&nbsp;highway funds and thwart drastic cuts to Medicare reimbursements.&nbsp;This morning, Bunning again blocked the Senate&nbsp;from taking up...]]></summary>
    <author>
        <name>bmartin</name>
        <uri>http://www.pathophilia.com</uri>
    </author>
    
        <category term="Health care" scheme="http://www.sixapart.com/ns/types#category" />
    
    <category term="medicare" label="Medicare" scheme="http://www.sixapart.com/ns/types#tag" />
    
    <content type="html" xml:lang="en" xml:base="http://bmartinmd.com/">
        <![CDATA[ Senator Bunning (R-KY) remains steadfast in his one-person crusade to block the passage of a bandaid bill that would extend unemployment benefits and&nbsp;highway funds and thwart drastic cuts to Medicare reimbursements.&nbsp;This morning, Bunning again blocked the Senate&nbsp;from taking up...]]>
        
    </content>
</entry>

<entry>
    <title>Conflicting Results of Carotid-Stent Trials Frustrate Practical Application</title>
    <link rel="alternate" type="text/html" href="http://bmartinmd.com/2010/03/conflicting-carotid-stent-trials.html" />
    <id>tag:bmartinmd.com,2010://1.778</id>

    <published>2010-03-01T16:08:47Z</published>
    <updated>2010-03-01T16:48:57Z</updated>

    <summary> Stenting of the carotid artery is a less invasive and potentially safer alternative to traditional endarterectomy (CEA) for the treatment of stenotic plaque. However, the relative efficacy of carotid stenting to prevent stroke has been unclear—a fact that has...</summary>
    <author>
        <name>bmartin</name>
        <uri>http://www.pathophilia.com</uri>
    </author>
    
        <category term="Neurology" scheme="http://www.sixapart.com/ns/types#category" />
    
    <category term="stroke" label="stroke" scheme="http://www.sixapart.com/ns/types#tag" />
    
    <content type="html" xml:lang="en" xml:base="http://bmartinmd.com/">
         Stenting of the carotid artery is a less invasive and potentially safer alternative to traditional endarterectomy (CEA) for the treatment of stenotic plaque. However, the relative efficacy of carotid stenting to prevent stroke has been unclear—a fact that has...
        
    </content>
</entry>

<entry>
    <title>Kick-Back Friday: #106</title>
    <link rel="alternate" type="text/html" href="http://bmartinmd.com/2010/02/kickback-friday-106.html" />
    <id>tag:bmartinmd.com,2010://1.780</id>

    <published>2010-02-27T00:02:11Z</published>
    <updated>2010-02-27T02:33:22Z</updated>

    <summary> The Honeymoon Killers (1969): It just goes to show you that a shoestring budget doesn&apos;t prevent the creation of really interesting shots. Director Leonard Castle and DP Oliver Wood are largely responsible for the look, sound, and feel of...</summary>
    <author>
        <name>bmartin</name>
        <uri>http://www.pathophilia.com</uri>
    </author>
    
        <category term="Kick-Back Friday" scheme="http://www.sixapart.com/ns/types#category" />
    
    <category term="kickbackfriday" label="Kick-Back Friday" scheme="http://www.sixapart.com/ns/types#tag" />
    <category term="movie" label="movie" scheme="http://www.sixapart.com/ns/types#tag" />
    
    <content type="html" xml:lang="en" xml:base="http://bmartinmd.com/">
         The Honeymoon Killers (1969): It just goes to show you that a shoestring budget doesn&apos;t prevent the creation of really interesting shots. Director Leonard Castle and DP Oliver Wood are largely responsible for the look, sound, and feel of...
        
    </content>
</entry>

<entry>
    <title>Senator Bunning: Persona Non Grata Among Practicing Physicians</title>
    <link rel="alternate" type="text/html" href="http://bmartinmd.com/2010/02/bunning-persona-non-grata.html" />
    <id>tag:bmartinmd.com,2010://1.779</id>

    <published>2010-02-26T19:24:25Z</published>
    <updated>2010-02-27T00:01:39Z</updated>

    <summary><![CDATA[ Doctors across the&nbsp;United States&nbsp;are throwing hate bombs in the direction of Kentucky, the home of Senator Jim Bunning. The ire&nbsp;is in response to the Senator's repeated objections yesterday and today to&nbsp;delay the upcoming 21% Medicare reimbursement cuts. The cuts&nbsp;are...]]></summary>
    <author>
        <name>bmartin</name>
        <uri>http://www.pathophilia.com</uri>
    </author>
    
        <category term="Health care" scheme="http://www.sixapart.com/ns/types#category" />
    
    <category term="healthcarereform" label="healthcare reform" scheme="http://www.sixapart.com/ns/types#tag" />
    
    <content type="html" xml:lang="en" xml:base="http://bmartinmd.com/">
        <![CDATA[ Doctors across the&nbsp;United States&nbsp;are throwing hate bombs in the direction of Kentucky, the home of Senator Jim Bunning. The ire&nbsp;is in response to the Senator's repeated objections yesterday and today to&nbsp;delay the upcoming 21% Medicare reimbursement cuts. The cuts&nbsp;are...]]>
        
    </content>
</entry>

</feed>

